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Electronic cigarettes for smoking cessation: a randomised controlled trial [E-Cigarette Research]
research:documents:pdn5xkgj
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Electronic cigarettes for smoking cessation: a randomised controlled trial

Journal Article 1)

Background:
Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping smokers to quit.

Findings:
657 people were randomised (289 to nicotine e-cigarettes, 295 to patches, and 73 to placebo e-cigarettes) and were included in the intention-to-treat analysis. At 6 months, verified abstinence was 7·3% (21 of 289) with nicotine e-cigarettes, 5·8% (17 of 295) with patches, and 4·1% (three of 73) with placebo e-cigarettes.

we had insufficient statistical power to conclude superiority of nicotine e-cigarettes to patches or to placebo e-cigarettes.

Interpretation:
E-cigarettes, with or without nicotine, were modestly effective at helping smokers to quit, with similar achievement of abstinence as with nicotine patches, and few adverse events. Uncertainty exists about the place of e-cigarettes in tobacco control, and more research is urgently needed to clearly establish their overall benefits and harms at both individual and population levels.

“.. insufficient statistical power to conclude superiority ..”
Let's see, 7.2% vs. 5.8%. Hmm.
And regardless, there were apparently enough statistics to conclude that they were effective, even if they were as modestly effective as patches.


z-ref: pdn5xkgj

1)
Bullen , et al. (2013), Electronic cigarettes for smoking cessation: a randomised controlled trial, http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)61842-5/fulltext accessed: 2013-09-13
research/documents/pdn5xkgj.txt · Last modified: 2014/03/29 01:54 by rainman