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A fresh look at tobacco harm reduction: the case for the electronic cigarette Journal Article Abstract Smokers of any age can reap substantial health benefits by quitting. In fact, no other single public health effort is likely to achieve a benefit comparable to large-scale smoking cessation. Surveys document that most smokers would like to quit, and many have made repeated efforts to do so. However, conventional smoking cessation approaches require nicotine addicted smokers to abstain fro…
A prospective cohort study challenging the effectiveness of population-based medical intervention for smoking cessation Journal Article Objective To examine the population effectiveness of nicotine replacement therapies (NRTs), either with or without professional counselling, and provide evidence needed to better inform healthcare coverage decisions.
A Systematic Review of Nicotine by Inhalation: Is There a Role for the Inhaled Route? Journal Article Introduction: A considerable minority of adults remain addicted to smoking cigarettes despite substantial education and public health efforts. Nicotine replacement therapies have only modest long-term quit rates. The pulmonary route of nicotine delivery has advantages over other routes. However, there are regulatory and technical barriers to the development of pulmonary nicotine delivery de…
Acute effects of electronic and tobacco cigarette smoking on complete blood count Journal Article The World Health Organisation called for research assessing the safety of electronic cigarette (e-cigarette). We evaluated the acute effect of active and passive e-cigarette and tobacco cigarette smoking on complete blood count (
Analysis of Electronic Cigarette Cartridges, Refill Solutions, and Smoke for Nicotine and Nicotine Related Impurities Journal Article The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination.
Analysis of refill liquids for electronic cigarettes Journal Article AIMS: To assess levels of nicotine, nicotine degradation products and some specific impurities in commercial refill liquids for electronic cigarettes. DESIGN AND SETTING: We analyzed 20 models of 10 of the most popular brands of refill liquids, using gas and liquid chromatography.
ASSESSMENT OF THIRDHAND EXPOSURE TO NICOTINE FROM ELECTRONIC CIGARETTES Conference Paper Purpose: Electronic cigarettes (e-cigarettes) are new battery-powered devices that resemble tobacco cigarettes and convert nicotine solutions into inhalable vapors.
Background Paper on E-Cigarettes Article OVERALL SUMMARY While most discussion of e-cigarettes among health authorities has concentrated on the product itself, its potential toxicity and use of e-cigarettes to help people quit smoking, the e- cigarette companies have been rapidly expanding using aggressive marketing messages similar to those used to promote cigarettes in the 1950s and 1960s. Moreover, e-cigarette advertising is on television and radio in many countries that have long-banne…
CDC Online Newsroom - E-cigarette use more than doubles among U.S. middle and high school students from 2011-2012 Web Press Release E-cigarette use more than doubles among U.S. middle and high school students from 2011-2012 More than 75 percent of youth users smoke conventional cigarettes too.
Chapter 12 - Cognitive, affective and motivational effects of smoking Book Section Publisher Summary This chapter discusses cognitive, affective, and motivational effects of smoking. The individual differences at genetic, personality, affective, and cognitive levels relate to the development of dependence and influence the effects of pharmacological and psychological interventions. It is found that smokers obtain benefits from nicotine, relative to their functioning when acutely abstinent,…
Characterization of chemicals released to the environment by electronic cigarettes use (ClearStream-AIR project): is passive vaping a reality? Journal Article Background Electronic cigarettes (e-CIG) have been marketed as a safer alternative habit to tobacco smoking. We have developed a group of research protocols to evaluate the effects of e-CIG on human health, called ClearStream. No studies have adequately evaluated the effects of e-CIG use on the release of chemicals to the environment…
Commentary on Etter & Bullen (2011): Could E-cigs become the ultimate nicotine maintenance device? Journal Article Smoked tobacco products are the only legal products that kill half their consumers, and some of those around them, when used as intended. More than 17 billion cigarettes are smoked world-wide every day, and that number continues to increase [1]. People smoke for the psychoactive and addictive effects of nicotine, but are killed by other toxins in the smoke [2,3].
Comparison of the aerosol produced by electronic cigarettes with conventional cigarettes and the shisha Journal Article In previous studies of the smoke from regular cigarettes and water pipes, we measured aerosol particle sizes in three streams; S1, inhaled by the smoker, S2, released by the device itself and
Comparison of the Cytotoxic Potential of Cigarette Smoke and Electronic Cigarette Vapour Extract on Cultured Myocardial Cells Journal Article Background: Electronic cigarettes (ECs) have been marketed as an alternative-to-smoking habit. Besides chemical studies of the content of
Comparison of the effects of e-cigarette vapor and cigarette smoke on indoor air quality Journal Article CONTEXT: Electronic cigarettes (e-cigarettes) have earned considerable attention recently as an alternative to smoking tobacco, but uncertainties about their impact on health and indoor air quality have resulted in proposals for bans on indoor e-cigarette use. OBJECTIVE: To assess potential health impacts relating to the use of e-cigarettes, a series of studies were conducted using e-ci…
Critical Review of “Background Paper on E-Cigarettes” Prepared for the World Health Organization by Grana, Benowitz, and Glantz. Analytical Observation It has become apparent that many legislators and public health experts are relying on Background Paper On E-Cigarettes prepared for the World Health Organization by Rachel Grana, Neal Benowitz, and
Determination of the Nicotine Content of Various Edible Nightshades (Solanaceae) and Their Products and Estimation of the Associated Dietary Nicotine Intake Journal Article This investigation was initiated as a result of proposals in the literature that dietary nicotine intake could contribute to the level of nicotine metabolites in biological fluids such as salivary cotinine concentration.
Does e-cigarette consumption cause passive vaping? Journal Article Electronic cigarette consumption ('vaping') is marketed as an alternative to conventional tobacco smoking. Technically, a mixture of chemicals containing carrier liquids, flavors, and optionally nicotine is vaporized and inhaled. The present study aims at the determination of the release of volatile organic compounds (
Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial Journal Article Objectives To measure the short-term effects of an electronic nicotine delivery device (“e cigarette”,
Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study Journal Article Cigarette smoking is a tough addiction to break. Therefore, improved approaches to smoking cessation are necessary.
Electronic cigarettes as a harm reduction strategy for tobacco control: A step forward or a repeat of past mistakes? Journal Article Abstract The issue of harm reduction has long been controversial in the public health practice of tobacco control. Health advocates have been reluctant to endorse a harm reduction approach out of fear that tobacco companies cannot be trusted to produce and market products that will reduce the risks associated with tobacco use.
Electronic cigarettes as a method of tobacco control Journal Editorial Article Allow them, but research and monitoring are needed so that the risks can be regulated. Electronic cigarettes (e-cigarettes), cigarette shaped products that vaporise nicotine in ways that enable it to be inhaled, have become increasingly popular in the past few years.
Electronic cigarettes for smoking cessation: a randomised controlled trial Journal Article Background: Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping smokers to quit.
Electronic Cigarettes: Effective Nicotine Delivery After Acute Administration Journal Article Introduction: Electronic cigarettes (ECs) are marketed as nicotine delivery devices. Two studies with EC-naïve participants suggest that ECs deliver little or no nicotine. In those studies, standard-sized ECs were used, though experienced
Electronic cigarettes: no adverse effects on blood and oxygen supply to the heart Web Page 31 August 2013 19:28 Electronic cigarette use does not cause any immediate adverse effects on coronary circulation and oxygen supply to the heart, according to a new study
Electronic Cigarettes: What We Know So Far Online video and PowerPoint presentation Summary ---------- z-ref: a8utrzsg 2nd_hand leans-neutral leans-positive carcinogens category-efficacy category-general information category-health_and_safety e-cigarette glycerin glycols nicotine pg propylene_glycol research smoking_cessation thr toxicity uk
Electronic nicotine delivery system (electronic cigarette) awareness, use, reactions and beliefs: a systematic review Journal Article Objective We sought to systematically review the literature on electronic nicotine delivery systems (ENDS, also called electronic cigarettes) awareness, use, reactions and beliefs. Data sources We searched five databases for articles published between 2006 and 1 July 2013 that contained variations of the phrases ‘electronic cigarette’, ‘e-cigarette’ and ‘elec…
Electronic Nicotine Delivery Systems: International Tobacco Control Four-country Survey Journal Article BACKGROUND: Electronic nicotine delivery systems (ENDS) initially emerged in 2003 and have since become widely available globally, particularly over the Internet. PURPOSE: Data on ENDS usage patterns are limited. The current paper examines patterns of ENDS awareness, use, and product-associated beliefs among current and former smokers in four countries.
Evaluating Nicotine Levels Selection and Patterns of Electronic Cigarette Use in a Group of "Vapers" Who Had Achieved Complete Substitution of Smoking Journal Article Background: Electronic cigarettes (ECs) are alternative-to-smoking nicotine delivery devices; consumers (commonly called vapers) use them in order to reduce or completely substitute smoking. The European Commission has released a proposal for a new Tobacco Product Directive that might reduce availability of nicotine-containin…
Evaluation of the cytotoxic potential of e-cigarette vapor on cultured cardiac cells: a new study Web Page Wednesday, 16 October 2013 12:20 A new study on electronic cigarettes was published today in International Journal of Environmental Research and Public Health. Researchers from Onassis Cardiac Surgery Center in Greece and Abich Toxicological Laboratory in Italy, lead by principle investigator Dr Konstantinos Farsalinos evaluated the cytotoxic potential of 20 different e-cigarette liq…
Evidence against a gateway from smokeless tobacco use to smoking Journal Article INTRODUCTION: It has been suggested that smokeless tobacco (ST) use by young people induces them to become smokers, but direct evidence is lacking. METHODS: Information in the 2003, 2005, and 2007 National Survey on Drug Use and Health was used to determine the prevalence of smoking among White men (aged 18+ years) and boys (aged 16-17 years) who had started tobacco use with ST, cigarettes, or with both produc…
Exposure of the us population to environmental tobacco smoke: The third national health and nutrition examination survey, 1988 to 1991 Journal Article Objective.  To estimate the extent of exposure of the US population to environmental tobacco smoke and the contribution of the home and workplace environment to environmental tobacco smoke exposure.
FAMILY SMOKING PREVENTION AND TOBACCO CONTROL ACT (FSPTCA) Statute An Act To protect the public health by providing the Food and Drug Administration with certain authority to regulate tobacco products, to amend title 5, United States Code, to make certain modifications in the Thrift Savings Plan, the Civil Service Retirement System, and the Federal Employees’ Retirement System, and for other purposes.
Free Market Solutions in Health: The case of nicotine Report Summary: Many campaigners working in the field of public health believe that good health and free market capitalism are irreconcilable. They regard advertising, competition and the pursuit of profit as major causes of unhealthy consumption and view disfavoured industries as ‘disease vectors’. Accordingly, they support political action which limits commercial speech and restricts product development.
Ground-breaking study supports e-cigarettes' superiority over nicotine patches | American Council on Science and Health (ACSH) Magazine Article In the first head-to-head comparison between e-cigarettes and nicotine patches (NRT) for helping smokers quit, a significant win for e-cigarettes was found in every measured parameter. Led by Dr. Chris Bullen of the University of Auckland, New Zealand, the researchers recruited 657 smokers who said that they wanted to quit. They were randomized into…
How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century - Springer Journal Article The discrepancy between the 60-mg dose and published cases of nicotine intoxication has been noted previously (Matsushima et al. 1995; Metzler et al. 2005), but nonetheless, this value is still accepted without scrutiny and taken as the basis for worldwide safety regulations of tobacco and other nicotine-containing products. Nicoti…
IDENTIFICATION OF CYTOTOXIC CHEMICALS IN THIRDHAND SMOKE Conference Paper (See note attachment for extended abstract) IDENTIFICATION OF CYTOTOXIC CHEMICALS IN THIRDHAND SMOKE Vasundhra Bahl*1,2, Suzaynn Schick 3, Mohamad Sleiman4, and Prue Talbot
Immediate effects of electronic cigarette use on coronary circulation and blood carboxyhemoglobin levels: comparison with cigarette smoking Journal Article Purpose: Cigarette smoking causes an acute elevation in carboxyhemoglobin levels (HbCO) and has immediate adverse effects on coronary circulation. The goal of this study was to evaluate the effects of electronic cigarette (
Impact of an Electronic Cigarette on Smoking Reduction and Cessation in Schizophrenic Smokers: A Prospective 12-Month Pilot Study Journal Article Abstract: Background: Cigarette smoking is a tough addiction to break. This dependence is the most common dual diagnosis for individuals with schizophrenia. Currently three effective drugs are approved for smoking cessation: nicotine replacement therapy (NRT), varenicline and bupropion. However, some serious side effects of varenicline have been…
Interviews With “Vapers”: Implications for Future Research With Electronic Cigarettes Journal Article Introduction: Awareness and use of electronic cigarettes (e-cigs) has increased dramatically. Electronic Nicotine Delivery Devices deliver an aerosol comprised usually of water, propylene glycol and/or glycerin, nicotine, and flavorings. Scant research exists to evaluate the efficacy and safety of such devices, and only one quantitative survey of European users (N = 81) has been published. …
Intravenous Nicotine and Caffeine: Subjective and Physiological Effects in Cocaine Abusers Journal Article The subjective and physiological effects of intravenously administered caffeine and nicotine were compared in nine subjects with histories of using caffeine, tobacco, and cocaine.
Investigating the impact of nicotine on executive functions using a novel virtual reality assessment Journal Article Aims Nicotine is known to enhance aspects of cognitive functioning in abstinent smokers, but the effects on specific areas of executive functions and in non-smokers are inconclusive. This may be due in part to the poor sensitivity of tests used to assess executive functions. This study used a new virtual reality assessment of executive functions known as JEF (the Jansari asse…
Is Nicotine a Carcinogen? Report Nicotine itself has not been given a cancer rating, and it has not been analyzed as a carcinogen in its pure form. Although researchers call it the most biologically active ingredient in tobacco smoke and chewing tobacco, nicotine itself, according to research, does not cause the cell mutations.
Is there any legal and scientific basis for classifying electronic cigarettes as medications? Journal Article The rapid growth in the use of electronic cigarettes has been accompanied by substantial discussions by governments, international organisations, consumers and public health experts about how they might be regulated.
Key Nicotine Findings.pdf Report Nicotine vs. tobacco smoke The main adverse effect of nicotine is addiction, which sustains tobacco use. Because most smokers are nicotine-dependent, they continue to expose themselves to toxicants from tobacco. Tobacco, not nicotine, is responsible for most of the adverse health effects.
Letter re fatal flaws in Schober et al. paper on environmental vapor Blog Post by Carl V Phillips Below is a letter to the editor and Igor Burstyn and I will be submitting to the journal that published this article -- “Use of electronic cigarettes (e-cigarettes) impairs indoor air quality and increases FeNO levels of e-cigarette consumers” by Schober W, Szendrei K, Matzen W, Osiander-Fuchs H, Heitmann D, Schettgen T, Jörres RA, Fromme H – which made alarmist claims about the content of exh…
Levels of selected carcinogens and toxicants in vapour from electronic cigarettes Journal Article Significance Electronic cigarettes, also known as e-cigarettes, are devices designed to imitate regular cigarettes and deliver nicotine via inhalation without combusting tobacco. They are purported to deliver nicotine without other toxicants and to be a safer alternative to regular cigarettes. However, little toxicity testing has been performed to evaluate the chemical nature of vapour generat…
Long-term effects of inhaled nicotine Journal Article Tobacco smoking has been reported to be associated with increased risk of cardiovascular disease and cancer, particularly of the lungs. In spite of extensive research on the health effects of tobacco smoking, the substances in tobacco smoke exerting these negative health effects are not completely known. Nicotine is the substance giving the subjective pleasure of smoking as well as inducing addiction.
Metabolism and Disposition Kinetics of Nicotine Journal Article Abstract Nicotine is of importance as the addictive chemical in tobacco, pharmacotherapy for smoking cessation, a potential medication for several diseases, and a useful probe drug for phenotyping cytochrome P450 2A6 (CYP2A6). We review current knowledge about the metabolism and disposition kinetics of nicotine, some other naturally occurring tobacco alkaloids, and nicotine analogs that are under development as potential thera…
Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats Journal Article Nicotine is the major neuroactive compound of tobacco, which has, by itself, weak reinforcing properties. It is known that levels of the enzymes monoamine oxidase A (MAO-A) and MAO-B are reduced in the platelets and brains of smokers and that substances, other than nicotine, present in tobacco smoke have MAO-inhibitory activities.
More on the Nicotine Content of Vegetables Article-Journal Review Commentary To the editor: Domino et al. (Aug 5 issue) suggest that nicotine obtained from the consumption of vegetables could complicate the interpretation of studies of exposure to environmental tobacco smoke based on the detection of nicotine or its metabolite cotinine. The crux of their argument was that typical levels of vegetable consumption could result in an exposure to nicotine equivalent to that from inhalation of …
New Study of Passive Vaping Shows No Evidence of a Significant Public Health Hazard Blog Post A new study published online ahead of print in the International Journal of Hygiene and Environmental Health is one of the first to examine levels of chemicals in the ambient air of a real-life setting in the presence of electronic cigarette use.
New Study Shows that Thirdhand Smoke is 100 Times More Dilute than Secondhand Smoke Blog Post What may be the first investigation to actually measure the ambient levels of thirdhand smoke and compare them with levels of secondhand smoke, a new study
Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices Journal Article A wide range of electronic cigarette (EC) devices, from small cigarette-like (first-generation) to new-generation high-capacity batteries with electronic circuits that provide high energy to a refillable atomizer, are available for smokers to substitute smoking.
Nicotine Addiction Journal Article This review gives an account of the cigarette as a highly efficient nicotine delivery system. It explains how nicotine induces pleasure, reduces stress and anxiety, and causes addiction to tobacco smoking. The basis of nicotine addiction rests on its effects on the brain, but addiction is also influenced by learned or conditioned factors, genetics, and social and environmental conditions.
Nicotine addiction and withdrawal Web Document . . . . Causes, incidence, and risk factors Tobacco is a plant grown for its leaves, which are smoked, chewed, or sniffed for a variety of effects. It is considered an addictive substance because it contains the chemical nicotine.
Nicotine and Health Blog Post This year, how about making a truly meaningful, life-altering New Year’s resolution? If you’re one of 44 million American smokers, we have one for you: Try separating the smoke from your nicotine fix. Doing so will save your life.
Nicotine Levels in Electronic Cigarettes Journal Article Introduction: The electronic cigarette (EC) is a plastic device that imitates conventional cigarettes and was developed to deliver nicotine in a toxin-free vapor. Nicotine in a solution is heated and
Nicotine treatment of mild cognitive impairment Journal Article Objective: To preliminarily assess the safety and efficacy of transdermal nicotine therapy on cognitive performance and clinical status in subjects with mild cognitive impairment (MCI).
Nicotine, the Wonder Drug? Magazine Article This notorious stimulant may enhance learning and help treat Parkinson's, schizophrenia and other neurological diseases. By Dan Hurley Wednesday, February 05, 2014 Nicotine delivery devices like the patch could offer surprising benefits to people diagnosed with certain neurological disorders.
Nicotine: Carcinogenic Potency Database (CPDB) Webpage, Document Nicotine is listed as non-carcenogenic in the NIH Carcinogenic Potency Database (CPDB) Rats and Mice: Cancer Test Summary Rat Target Sites Mouse Target Sites
Patterns of change in withdrawal symptoms, desire to smoke, reward motivation and response inhibition across 3 months of smoking abstinence Journal Article Aims We have demonstrated previously that acute smoking abstinence is associated with lowered reward motivation and impaired response inhibition. This prospective study explores whether these impairments, along with withdrawal-related symptoms, recover over 3 months of sustained abstinence.
Patterns of tobacco-related mortality among individuals diagnosed with schizophrenia, bipolar disorder, or depression Journal Article Abstract Even though individuals with psychiatric conditions have a prevalence of smoking approximately 2–4 times greater than the general population, surprisingly little evidence exists to inform an assessment of the full range of tobacco-related mortality in such populations.
Peering through the Mist: Systematic Review of What the Chemistry of Contaminants in Electronic Cigarettes Tells Us about Health Risks Article-Journal Background Electronic cigarettes (e-cigarettes) are generally recognized as a safer alternative to combusted tobacco products, but there are conflicting claims about the degree to which these products warrant concern for the health of the vapers (e-cigarette users). This paper reviews available data on chemistry of aerosols and liquids of elec…
Psychosocial Withdrawal Characteristics of Nicotine Compared with Alcohol and Caffeine Journal Article The purpose of the present study was to observe the psychosocial characteristics of withdrawal from cigarette smoking in comparison with those from caffeine (CAF) and alcoholic (ALC) beverage withdrawal.
RainMan's 2011-2012 CDC NYTS Survey Data Note: Data is preliminary, needs verification but believed to be accurate. Link to original CDC Datasets Related: CDC Online Newsroom - E-cigarette use more than doubles among U.S. middle and high school students from 2011-2012 category-youth cdc e-cigarette folder-e-cigs gateway incomplete_information-_bias leans-positive nicotine survey
Rapid Nicotine Clearance is Associated with Greater Reward and Heart Rate Increases from Intravenous Nicotine Journal Article The ratio of nicotine metabolites (trans-3′-hydroxycotinine (3HC) to cotinine) correlates with nicotine clearance. In previous studies, high nicotine metabolite ratio (NMR) predicted poor outcomes for smoking cessation treatment with nicotine patch. The underlying mechanisms that associate NMR with treatment outcomes have not been fully elucidated.
Secondhand Exposure to Vapors From Electronic Cigarettes Article-Journal Introduction: Electronic cigarettes (commonly referred as e-cigarettes) are designed to generate inhalable nicotine aerosol (vapor). When an e-cigarette user takes a puff, the nicotine solution is heated and the vapor taken into lungs.
Should criteria for drug dependence differ across drugs? Journal Article Aim To examine the pros and cons of using the same diagnostic criteria for dependence across all drugs versus using dependence criteria specific to the drug of interest.
Technical Review and Analysis of FDA Report:“Evaluation of e-cigarettes” Journal Article Summary A recent report and press release issued by the Food and Drug Administration (FDA) assert that NJOY e-cigarette cartridges contain harmful levels of carcinogens and toxic chemicals. It was further implied that these chemicals are not found in other FDA-approved nicotine-containing products. Subsequently, a technical review and scientific analysis of the FDA’s report was performed by scientists …
The effects of cigarette smoking and abstinence on auditory verbal learning Journal Article Smoking has been associated with both enhanced and impaired cognitive performance; across a variety of domains, but there is limited evidence demonstrating the effects on verbal learning.
The effects of nicotine on human health | American Council on Science and Health (ACSH) Document Summary MORTALITY RISKS AND CANCER RISKS VARY GREATLY BY PRODUCT Cigarettes and smoking tobacco are the most deadly recreation products on shop shelves. Nicotine has been widely used as a medicine since 1984 and is safe at the doses used in medicines. Nicotine products do not cause lung or other cancers, nor lung or heart disease. Tobacco smoking, in contrast, is the main cause of lung cancer a…
The Electronic Cigarette: What Proportion of Smokers Have Tried It and How Many Use It Regularly? Article-Journal We read with interest the article by Wagener et al. , which calls for a balanced analysis of the risks and benefits of e-cigarettes (
The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition Journal Article Electronic cigarettes (e-cigarettes) are battery operated devices that deliver nicotine via inhaled vapour. Few studies have evaluated acute effects on craving and mood, and none have explored effects on cognition.
The increasing prevalence in New Zealand of exposures of children to nicotine replacement therapies Conference Paper Objective: A review of calls to the New Zealand National Poisons Centre to determine if there is an increased incidence of children ingesting oral nicotine replacement therapies (NRTs).
The Nicotine Content of Common Vegetables Article-Journal Review Commentary To the Editor: The presence of nicotine and its metabolite cotinine in the body fluids of nonsmokers is usually taken as evidence of exposure to environmental tobacco smoke. Recently, the Centers for Disease Control and Prevention studied 800 people, both smokers and nonsmokers, all of whom tested positive for urinary cotinine1. There is considerable evidence that nicotine is present in certain human foods, especiall…
Three cases of attempted suicide by ingestion of nicotine liquid used in e-cigarettes Conference Paper (Ingestion of up to 1500ml of e-liquid solution by a 36 y.o. adult shown to be non-fatal) Objective: We report three cases (in two persons) concerning deliberate ingestion in attempted suicide. The Poisons Information Center in Denmark is experiencing an increasing number of calls concerning intake of nicotine liquid used for electronic cigarettes. Most cases concern accidental intake in…
Toxins in E-Cig Vapor Also Found in Human Breath and Outdoor Air Manuscript Summary * Five of the volatile organic compounds detected by various studies in electronic cigarette vapor have also been found in human breath emissions (acetaldehyde, acetone, butanone, formaldehyde and isoprene).
Treatment of nicotine addiction: present therapeutic options and pipeline developments Journal Article Tobacco use is a global pandemic that poses a substantial and costly health burden. There are some treatment options are available, but currently marketed smoking-cessation drugs lack high levels of efficacy, particularly in real-life settings. Consequently, there is a compelling need for more effective pharmacotherapies to aid smokers in maintaining long-term abstinence.
Use of electronic cigarettes (e-cigarettes) impairs indoor air quality and increases FeNO levels of e-cigarette consumers Journal Article Despite the recent popularity of e-cigarettes, to date only limited data is available on their safety for both users and secondhand smokers. The present study reports a comprehensive inner and outer exposure assessment of e-cigarette emissions in terms of particulate matter (