E-Cigarette Research

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Eissenberg , et al. (2010), A Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects,
Eissenberg , et al. (2010), A Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects,
A fresh look at tobacco harm reduction: the case for the electronic cigarette Journal Article Abstract Smokers of any age can reap substantial health benefits by quitting. In fact, no other single public health effort is likely to achieve a benefit comparable to large-scale smoking cessation. Surveys document that most smokers would like to quit, and many have made repeated efforts to do so. However, conventional smoking cessation approaches require nicotine addicted smokers to abstain fro…
A Systematic Review of Nicotine by Inhalation: Is There a Role for the Inhaled Route? Journal Article Introduction: A considerable minority of adults remain addicted to smoking cigarettes despite substantial education and public health efforts. Nicotine replacement therapies have only modest long-term quit rates. The pulmonary route of nicotine delivery has advantages over other routes. However, there are regulatory and technical barriers to the development of pulmonary nicotine delivery de…
Acute effects of electronic and tobacco cigarette smoking on complete blood count Journal Article The World Health Organisation called for research assessing the safety of electronic cigarette (e-cigarette). We evaluated the acute effect of active and passive e-cigarette and tobacco cigarette smoking on complete blood count (
Flouris , et al. (2013), Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function, <http://informahealthcare.com/doi/abs/10.3109/08958378.2012.758197> accessed: 2014-02-20
Trehy , et al. (2011), Analysis of Electronic Cigarette Cartridges, Refill Solutions, and Smoke for Nicotine and Nicotine Related Impurities,
Analysis of refill liquids for electronic cigarettes Journal Article AIMS: To assess levels of nicotine, nicotine degradation products and some specific impurities in commercial refill liquids for electronic cigarettes.
ASSESSMENT OF THIRDHAND EXPOSURE TO NICOTINE FROM ELECTRONIC CIGARETTES Conference Paper Purpose: Electronic cigarettes (e-cigarettes) are new battery-powered devices that resemble tobacco cigarettes and convert nicotine solutions into inhalable vapors.
G. Romagna MD , et al. (2012), Characterization of chemicals released to the environment by electronic cigarettes use (ClearStream-AIR project): is passive vaping a reality?,
Cigarette Smoke Toxins Deposited on Surfaces: Implications for Human Health Journal Article Cigarette smoking remains a significant health threat for smokers and nonsmokers alike. Secondhand smoke (
Farsalinos , et al. (2013), Comparison of the Cytotoxic Potential of Cigarette Smoke and Electronic Cigarette Vapour Extract on Cultured Myocardial Cells,
Comparison of the effects of e-cigarette vapor and cigarette smoke on indoor air quality Journal Article CONTEXT: Electronic cigarettes (e-cigarettes) have earned considerable attention recently as an alternative to smoking tobacco, but uncertainties about their impact on health and indoor air quality have resulted in proposals for bans on indoor e-cigarette use. OBJECTIVE: To assess potential health impacts relating to the use of e-cigarettes, a series of studies were conducted using e-ci…
Kim & Shin (2013), Determination of tobacco-specific nitrosamines in replacement liquids of electronic cigarettes by liquid chromatography–tandem mass spectrometry,
Does e-cigarette consumption cause passive vaping? Journal Article Electronic cigarette consumption ('vaping') is marketed as an alternative to conventional tobacco smoking. Technically, a mixture of chemicals containing carrier liquids, flavors, and optionally nicotine is vaporized and inhaled. The present study aims at the determination of the release of volatile organic compounds (
Bullen , et al. (2010), Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial,
Polosa , et al. (2011), Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study,
Caponnetto , et al. (2013), Efficiency and Safety of an electronic cigarette (ECLAT) as Tobacco Cigarettes Substitute: A Prospective 12-Month Randomized Control Design Study,
Cahn & Siegel (2011), Electronic cigarettes as a harm reduction strategy for tobacco control: A step forward or a repeat of past mistakes?,
Electronic cigarettes as a method of tobacco control Journal Editorial Article Allow them, but research and monitoring are needed so that the risks can be regulated.
Electronic cigarettes for smoking cessation: a randomised controlled trial Journal Article Background: Electronic cigarettes (e-cigarettes) can deliver nicotine and mitigate tobacco withdrawal and are used by many smokers to assist quit attempts. We investigated whether e-cigarettes are more effective than nicotine patches at helping smokers to quit.
Pellegrino , et al. (2012), Electronic cigarettes: an evaluation of exposure to chemicals and fine particulate matter (PM), <http://europepmc.org/abstract/MED/22913171/> accessed: 2014-02-17
Electronic Cigarettes: Effective Nicotine Delivery After Acute Administration Journal Article Introduction: Electronic cigarettes (ECs) are marketed as nicotine delivery devices. Two studies with
Electronic Cigarettes: What We Know So Far Online video and PowerPoint presentation Summary ---------- z-ref: a8utrzsg 2nd_hand leans-neutral leans-positive carcinogens category-efficacy category-general information category-health_and_safety e-cigarette glycerin glycols nicotine pg propylene_glycol research smoking_cessation thr toxicity uk
Pepper & Brewer (2013), Electronic nicotine delivery system (electronic cigarette) awareness, use, reactions and beliefs: a systematic review,
Electronic Nicotine Delivery Systems: International Tobacco Control Four-country Survey Journal Article BACKGROUND: Electronic nicotine delivery systems (ENDS) initially emerged in 2003 and have since become widely available globally, particularly over the Internet. PURPOSE: Data on ENDS usage patterns are limited. The current paper examines patterns of ENDS awareness, use, and product-associated beliefs among current and former smokers in four countries.
Farsalinos , et al. (2013), Evaluating Nicotine Levels Selection and Patterns of Electronic Cigarette Use in a Group of
Evidence against a gateway from smokeless tobacco use to smoking Journal Article INTRODUCTION: It has been suggested that smokeless tobacco (ST) use by young people induces them to become smokers, but direct evidence is lacking.
FDA and Public Health Experts Warn About Electronic Cigarettes - Press Announcement Press Announcement The U.S. Food and Drug Administration today announced that a laboratory analysis of electronic cigarette samples has found that they contain carcinogens and toxic chemicals such as diethylene glycol, an ingredient used in antifreeze.
Heat degradation studies of solar heat transfer fluids Journal Article Destructive distillation of solar heat transfer fluids was conducted to determine the types of pyrolytic products which might be formed in solar collectors under conditions of stagnation or malfunction.
How are the English Stop Smoking Services responding to growth in use of electronic cigarettes? Journal Article OBJECTIVE: To assess extent of electronic cigarette use by smokers attending Stop Smoking Services, the advice given about electronic cigarettes and whether this usage is recorded.
Mayer (2013), How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century - Springer,
IDENTIFICATION OF CYTOTOXIC CHEMICALS IN THIRDHAND SMOKE Conference Paper (See note attachment for extended abstract) IDENTIFICATION OF CYTOTOXIC CHEMICALS IN THIRDHAND SMOKE Vasundhra Bahl*
Interviews With “Vapers”: Implications for Future Research With Electronic Cigarettes Journal Article Introduction:
Dawkins , et al. (2013), Investigating the impact of nicotine on executive functions using a novel virtual reality assessment, <http://onlinelibrary.wiley.com/doi/10.1111/add.12082/abstract> accessed: 2013-11-11
Learning from Evidence in a Complex World Journal Article Policies to promote public health and welfare often fail or worsen the problems they are intended to solve. Evidence-based learning should prevent such policy resistance, but learning in complex systems is often weak and slow. Complexity hinders our ability to discover the delayed and distal impacts of interventions, generating unintended “side effects.”
Levels of selected carcinogens and toxicants in vapour from electronic cigarettes Journal Article Significance Electronic cigarettes, also known as e-cigarettes, are devices designed to imitate regular cigarettes and deliver nicotine via inhalation without combusting tobacco. They are purported to deliver nicotine without other toxicants and to be a safer alternative to regular cigarettes. However, little toxicity testing has been performed to evaluate the chemical nature of vapour generat…
Long-term effects of inhaled nicotine Journal Article Tobacco smoking has been reported to be associated with increased risk of cardiovascular disease and cancer, particularly of the lungs.
Guillem , et al. (2005), Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats,
Kozlowski , et al. (2003), Most smokeless tobacco use is not a causal gateway to cigarettes: using order of product use to evaluate causation in a national US sample,
Farsalinos , et al. (2014), Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices,
Nicotine Addiction Journal Article This review gives an account of the cigarette as a highly efficient nicotine delivery system. It explains how nicotine induces pleasure, reduces stress and anxiety, and causes addiction to tobacco smoking. The basis of nicotine addiction rests on its effects on the brain, but addiction is also influenced by learned or conditioned factors, genetics, and social and environmental conditions.
Nicotine Levels in Electronic Cigarettes Journal Article Introduction: The electronic cigarette (EC) is a plastic device that imitates conventional cigarettes and was developed to deliver nicotine in a toxin-free vapor. Nicotine in a solution is heated and
Nicotine treatment of mild cognitive impairment Journal Article Objective: To preliminarily assess the safety and efficacy of transdermal nicotine therapy on cognitive performance and clinical status in subjects with mild cognitive impairment (MCI).
Richardson , et al. (2013), Noncombustible Tobacco Product Advertising: How Companies Are Selling the New Face of Tobacco, <http://ntr.oxfordjournals.org/content/early/2013/12/29/ntr.ntt200> accessed: 2014-01-30
Dawkins , et al. (2009), Patterns of change in withdrawal symptoms, desire to smoke, reward motivation and response inhibition across 3 months of smoking abstinence,
Goniewicz , et al. (2013), Patterns of electronic cigarette use and user beliefs about their safety and benefits: an Internet survey,
Callaghan , et al. (2013), Patterns of tobacco-related mortality among individuals diagnosed with schizophrenia, bipolar disorder, or depression,
Burstyn, I. (2014) 'Peering through the mist: systematic review of what the chemistry of contaminants in electronic cigarettes tells us about health risks', BMC Public Health, 14: 18. <doi:10.1186/1471-2458-14-18>
Sofuoglu , et al. (2012), Rapid Nicotine Clearance is Associated with Greater Reward and Heart Rate Increases from Intravenous Nicotine,
Real–Time Measurement of Outdoor Tobacco Smoke Particles Journal Article Abstract The current lack of empirical data on outdoor tobacco smoke (OTS) levels impedes OTS exposure and risk assessments. We sought to measure peak and time-averaged OTS concentrations in common outdoor settings near smokers and to explore the determinants of time-varying OTS levels, including the effects of source proximity and wind. Using five types of real-time airborne particle monitoring devices, we obtained mo…
Secondhand Exposure to Vapors From Electronic Cigarettes Article-Journal Introduction: Electronic cigarettes (commonly referred as e-cigarettes) are designed to generate inhalable nicotine aerosol (vapor). When an e-cigarette user takes a puff, the nicotine solution is heated and the vapor taken into lungs.
Vardavas , et al. (2012), Short-term pulmonary effects of using an electronic cigarette: Impact on respiratory flow resistance, impedance, and exhaled nitric oxide,
Teen smoking continues to decline in 2013 Journal Article Teen smoking continues to decline in 2013 ANN ARBOR—Smoking among teens in grades 8, 10 and 12 continued to decline in 2013—apositive trend since most smokers begin their habit in adolescence—according to the latest survey results from the nationwide Monitoring the Future study.
Robertson , et al. (1947), Tests for the Chronic Toxicity of Propylexe Glycol and Triethylene Glycol on Monkeys and Rats by Vapor Inhalation and Oral Administration,
The effects of cigarette smoking and abstinence on auditory verbal learning Journal Article Smoking has been associated with both enhanced and impaired cognitive performance; across a variety of domains, but there is limited evidence demonstrating the effects on verbal learning.
The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition Journal Article Electronic cigarettes (e-cigarettes) are battery operated devices that deliver nicotine via inhaled vapour. Few studies have evaluated acute effects on craving and mood, and none have explored effects on cognition.
Benjamin Mason Meier, and Donna Shelley (10-2006) 'The Fourth Pillar of the Framework Convention on Tobacco Control: Harm Reduction and the International Human Right to Health', Public Health Reports, 121: 494 – 500,
THE MECHANISM OF AERIAL DISINFECTION BY GLYCOLS AND OTHER CHEMICAL AGENTS - 1 Journal Article Theoretical analysis of the mechanism of action of chemical aerial disinfectants reveals that the rapid killing action which is obtained cannot be accounted for by a collision process between germicidal aerosol particles and the air-borne bacteria. However, a mechanism involving condensation of germicide molecules in the vapor state on to the bacteria-containing droplets results in a theoretical ve…
THE MECHANISM OF AERIAL DISINFECTION BY GLYCOLS AND OTHER CHEMICAL AGENTS - 2 Journal Article The effectiveness of any compound as an aerial germicide depends upon the extent of condensation of its vapor on air-suspended bacteria, and on the rate at which the resulting concentration of germicide can produce death of the microorganisms. The properties of any compound conducive to production of the highest rate of kill of air-borne microorganisms by means of the smallest possible concentratio…
Tobacco harm reduction: How rational public policy could transform a pandemic Journal Article Nicotine, at the dosage levels smokers seek, is a relatively innocuous drug commonly delivered by a highly harmful device, cigarette smoke.
Sweanor, D., P. Alcabes, and E. Drucker (03-2007) 'Tobacco harm reduction: How rational public policy could transform a pandemic', International Journal of Drug Policy, 18: 70–74.
Use of a liquid nicotine delivery product to promote smoking cessation Journal Article Despite access to various pharmacotherapies and counseling support to aid cessation, smokers typically demonstrate quit rates below 50%. This report describes the results of a Phase 2a study exploring the efficacy of a liquid nicotine delivery system as an aid to smoking cessation assessed after 12 weeks of therapy. PMID: 20334673